t-Butyl 4-chloro-2-fluorobenzoate synthesis
- Product Name:t-Butyl 4-chloro-2-fluorobenzoate
- CAS Number:941294-14-0
- Molecular formula:C11H12ClFO2
- Molecular Weight:230.66
941294-14-0
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$60.00/1g
120120-26-5
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$14.00/250mg
1240100-16-6
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Yield:1240100-16-6 72%
Reaction Conditions:
with potassium fluoride;dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine;bis(dibenzylideneacetone)-palladium(0) in 1,4-dioxane at 130;
References:
Cho, Eun Jin;Senecal, Todd D.;Kinzel, Tom;Zhang, Yong;Watson, Donald A.;Buchwald, Stephen L. [Science,2010,vol. 328,# 5986,p. 1679 - 1681] Location in patent:scheme or table