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ChemicalBook CAS DataBase List Sodium citrate
68-04-2

Sodium citrate synthesis

4synthesis methods
Produced by the neutralization of citric acid with sodium hydroxide or sodium carbonate. May be prepared in an anhydrous state or may contain 2 mole of water per mole of sodium citrate.
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Yield:-

Reaction Conditions:

with sodium hydrogencarbonate in water;

Steps:

Method of Preparation of Final Active Composition for Use:

Mix one part of citric acid and one part of sodium bicarbonate than gradually spray in it, specific quantity of sterile water sufficiently to make it complete reaction and evaporate the water and carbon dioxide completely. The water is merely the medium for the reaction. Carbon dioxide is evaporated rapidly and water is gradually evaporated. The remaining product is a mixture of 87% Sodium citrate and 13% citric acid active ingredient (“SCCA”). The product is in the form of crystals. The product is then dried and crushed to fine particles to produce an SCCA composition. Zinc Sulphate (“ZS”) is now added into the active SCCA composition and the (weight/weight) ratio of SCCA and ZS will be 500 mg of SCCA with 25 mg of ZS (Zinc Sulfate) to produce the “active treatment composition”. This composition is then encapsulated for use in the treatment of COVID-19 in patients.

References:

US2021/346426,2021,A1 Location in patent:Paragraph 0038

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