Pyrrole synthesis

11synthesis methods

Product Name:Pyrrole
CAS Number:109-97-7
Molecular formula:C4H5N
Molecular Weight:67.09

By fractional distillation of bone oil (bone oil is obtained by destructive distillation of animal bone) and subsequent purification via the corresponding potassium salt; by thermal decomposition of ammonium mucate in glycerol or mineral oil.

110-00-9 Synthesis

110-00-9
210 suppliers
$10.00/25g

109-97-7
345 suppliers
$9.00/5G

Yield:109-97-7 99.8 %Chromat.

Reaction Conditions:

with ammonia at 320 - 360;Reagent/catalyst;Temperature;

Steps:

4

The SO₄^2-/TiO₂-SnO₂-Al₂O₃ type solid attached to a fixed bed, and with the airspeed at 0.075g / min introduced nitrogen for deaeration; when then fixed bed was heated to 320 ° C, then into the fixed bed passing ammonia, water vapor for 10min, at this time the fixed bed internal temperature was 360 ° C, and then into the fixed bed pass furan. The molar ratio of furan, ammonia and water vapor is 1: 8: 11. The total airspeed of furan, ammonia and water vapor is 1g / min; At the end of the reaction, stop the inletting of furan, and then continue to pass ammonia, water vapor for 10min; The reaction mixture is passed into a condensing unit at a temperature of -20 ° C; The mixed product is condensed and liquefied to a mixed liquid, then , added sodium hydroxide to adjust the pH to 12; Static stratification to obtain upper layer of the mixture and the lower lye; The distillation of the upper layer mixture was carried out at 80 ° C and recovering the distillated furan for recycling to obtain crude pyrrole; after the lower lye was concentrated , it was then recycled. The crude pyrrole was distilled to obtain pyrrole.

References:

CN106831527,2017,A Location in patent:Page/Page column 5-8