Phenylmethylsulfonyl fluoride synthesis
- Product Name:Phenylmethylsulfonyl fluoride
- CAS Number:329-98-6
- Molecular formula:C7H7FO2S
- Molecular Weight:174.19
1939-99-7
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329-98-6
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Yield:329-98-6 97%
Reaction Conditions:
with potassium fluoride;triethylamine in dichloromethane;water;
Steps:
18 EXAMPLE 18
EXAMPLE 18 A solution of 95.25 g (0.5 mol) of phenylmethanesulphonic acid chloride in 400 ml of methylene chloride is treated with a solution of 34.8 g (0.6 mol) of potassium fluoride in 80 ml of water. 10 g of triethylamine are added dropwise to the mixture at 25° C. After stirring for 3 hours at room temperature, the organic phase is separated off, dried with sodium sulphate and then freed from the solvent in a rotary evaporator. The residue is distilled in a high vacuum. This gives 84.5 g of phenylmethanesulphonic acid fluoride (boiling point0.5: 80 - 85° C; yield: 97%).
References:
US4060549,1977,A
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329-98-6
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329-98-6
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