ChemicalBook CAS DataBase List P-BROMOPHENACYL-8 P-BROMOPHENACYL BROMIDE/CROWN

P-BROMOPHENACYL-8 P-BROMOPHENACYL BROMIDE/CROWN synthesis

4synthesis methods

Product Name:P-BROMOPHENACYL-8 P-BROMOPHENACYL BROMIDE/CROWN
CAS Number:65679-14-3
Molecular formula:C9H6BrNOS
Molecular Weight:256.12

333-20-0
447 suppliers
$13.50/100G

99-73-0 Synthesis

99-73-0
232 suppliers
$10.00/1g

P-BROMOPHENACYL-8 P-BROMOPHENACYL BROMIDE/CROWN

65679-14-3
36 suppliers
$30.00/1g

Yield:65679-14-3 98%

Reaction Conditions:

in ethanol at 20; for 5 h;

Steps:

1.1

Step 1: 2-(4-Bromophenyl)-2-oxoethyl thiocyanate A mixture of 2,4'-dibromoacetophenone (56.08 g, 0.20 mol) and potassium thiocyanate (21.57 g, 0.22 mol) in 1 L of absolute ethanol was stirred under nitrogen at room temperature for 5 h. The reaction was added to 2 L of water and the mixture stirred at room temperature for 2 h. The solid present was collected by filtration, rinsed with water, ice-cold ethanol, hexane, and then dried under high vacuum to give 2-(4-bromophenyl)-2-oxoethyl thiocyanate (50.39 g, 98%) as a white solid, mp 148-149° C.

References:

US2008/45518,2008,A1 Location in patent:Page/Page column 14

540-72-7 Synthesis