ChemicalBook CAS DataBase List Nalpha-Cbz-L-Arginine

Nalpha-Cbz-L-Arginine synthesis

7synthesis methods

Product Name:Nalpha-Cbz-L-Arginine
CAS Number:1234-35-1
Molecular formula:C14H20N4O4
Molecular Weight:308.33

420-04-2 Synthesis

420-04-2
351 suppliers
$15.00/25g

2640-58-6 Synthesis

2640-58-6
127 suppliers
$7.00/250mg

1234-35-1
269 suppliers
$5.00/1g

Yield:1234-35-1 68%

Reaction Conditions:

with scandium tris(trifluoromethanesulfonate) in water at 100; for 24 h;

Steps:

General Procedure for the Guanylation of Amines:
General procedure: To a solution of p-methoxyaniline (1b, 61.6 mg, 0.50 μmol)and cyanamide (25.2 mg, 0.60 μmol) in H2O (2.5 mL) wasadded Sc(OTf)3 (24.6 mg, 50 nmol) at r.t. After the solutionwas stirred at 100 °C for 2 d, the resulting mixture waswashed with CHCl3 (3 × 10 mL). The aqueous layer wasconcentrated in vacuo, and the residue was purified by filtering through silica gel pad (CHCl3-MeOH, 20:1).

References:

Tsubokura, Kazuki;Iwata, Takayuki;Taichi, Misako;Kurbangalieva, Almira;Fukase, Koichi;Nakao, Yoichi;Tanaka, Katsunori [Synlett,2014,vol. 25,# 9,p. 1302 - 1306]

FullText

74-79-3 Synthesis