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ChemicalBook CAS DataBase List Methyl methacrylate
80-62-6

Methyl methacrylate synthesis

13synthesis methods
Prepared by the esterification of methacrylamide sulfate with methanol.
-

Yield:80-62-6 99.7%

Reaction Conditions:

with 1.5 % Au/alumina;oxygen at 60; under 9034.64 Torr;Catalytic behavior;chemoselective reaction;

Steps:

1 Example 1

A series of runs was conducted in which 20 wt% methacrolein, 200 ppm inhibitor, and a balance of methanol were fed to a 3/8" (9.5 mm) stainless steel tubular reactor containing a short front section of silica carbide followed by 10 g of catalyst. The catalyst consisted of 1.5 wt% Au on a Norpro 1 mm diameter high surface area alumina spherical support. The Au is primarily located near the outer edge of the catalyst within 150 microns of the outer edge. A gas containing 8% oxygen in nitrogen was also feed to the reactor. The reactor was operated at 60 °C and 160 psig (1200 kPa). The product of the reactor was sent to a liquid- vapor separator and the vapor was sent to a condenser with liquid return. A portion of the product stream from this separator was recycled in some cases to the reactor inlet and combined with the feed entering the reactor. Results are described in the below table. MIB is reported in ppm on a 100% MMA product basis. Product MMA is the percent MMA among products originating as methacrolein reactant. (0032) Prod Vent Gas (0033) MMA Conv MIB Feed Recycle O2 Gas Type (0034) (%) (%) (ppm) (g/hr) (g/hr) (mol%) (SCCM) (0035) 99.7 8.0 1170 100 0 0.2 75 8% 02 (0036) 96.4 10.5 670 200 0 1.9 200 8% 02 (0037) 97.6 17.9 540 100 100 2.3 200 8% 02 (0038) 97.9 14.4 540 200 0 2.6 500 8% 02 (0039) 98.0 24.7 470 100 100 3.1 500 8% 02 (0040) 97.8 75.8 460 20 0 4 450 8% 02 (0041) Examples of the effect of eggshell vs uniform catalyst loading are provided below.

References:

WO2019/22888,2019,A1 Location in patent:Page/Page column 6

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