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215436-29-6

Methyl 5-(tert-butyl)picolinate synthesis

2synthesis methods
-

Yield:1465282-71-6 59% ,215436-29-6 7%

Reaction Conditions:

Stage #1: methanol;benzene-1,2-diolwith pyridine;oxygen;1,4,7-triazacyclononane;iron(II) bromide for 16 h;Inert atmosphere;
Stage #2: with ammonium formate at 60; for 48 h;

References:

Guimond, Nicolas;Mayer, Peter;Trauner, Dirk [Chemistry - A European Journal,2014,vol. 20,# 31,p. 9519 - 9523] Location in patent:supporting information