ChemicalBook CAS DataBase List m-Toluic acid

m-Toluic acid synthesis

13synthesis methods

Product Name:m-Toluic acid
CAS Number:99-04-7
Molecular formula:C8H8O2
Molecular Weight:136.15

620-22-4 Synthesis

620-22-4
224 suppliers
$14.00/25mL

99-04-7
450 suppliers
$8.00/100g

Yield:99-04-7 98.5%

Reaction Conditions:

with water;sodium hydroxide at 100; for 4 h;Temperature;

Steps:

1-3

To 2000ml with mechanical stirring, thermometer, reflux condenser, add 117g of m-toluonitrile, 800g of water, and 200g of sodium hydroxide solution with a mass fraction of 30% to the four-neck flask of the heating device, and start stirring. The temperature was raised to 100 °C and the reaction was carried out under reflux for 4h. Then, hydrochloric acid with a mass fraction of 30% was added dropwise to adjust the pH to 1. After cooling to room temperature, it was filtered, washed with water, filter and dry to get 134g m-toluic acid, the reaction yield at this step was 98.5%.

References:

CN110981719,2020,A Location in patent:Paragraph 0040-0041; 0045-0046; 0050-0051