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ChemicalBook CAS DataBase List IFLAB-BB F2108-0089
284462-78-8

IFLAB-BB F2108-0089 synthesis

6synthesis methods
N-methyl-4-(3-nitrophenoxy)-2-Pyridinecarboxamide

827029-02-7
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IFLAB-BB F2108-0089

284462-78-8
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Yield:284462-78-8 92%

Reaction Conditions:

with hydrogen;nickel in tetrahydrofuran;methanol at 20;

Steps:

1

The thus obtained product is hydrogenated at room temperature using Raney-nickel in MEOH/THF. The reaction solution is filtered through A Seitz-filter, rinsed with MEOH and the filtrate is subsequently evaporated. The residue is taken up in DICHLOROMETHANE, dried over Na2SO4, filtered and evaporated. Yield : 2. 29 g (92 %) 5G, brown oil

References:

WO2005/4863,2005,A1 Location in patent:Page/Page column 132

220000-87-3 Synthesis
4-Chloro-N-methylpicolinamide

220000-87-3
470 suppliers
$8.00/5g

IFLAB-BB F2108-0089

284462-78-8
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