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ChemicalBook CAS DataBase List CIS-15-OCTADECENOIC ACID METHYL ESTER
10411-39-9

CIS-15-OCTADECENOIC ACID METHYL ESTER synthesis

3synthesis methods
-

Yield:10411-39-9 80%

Reaction Conditions:

Stage #1: n-propyltriphenylphosphonium bromidewith sodium hexamethyldisilazane in tetrahydrofuran at 0 - 20;Inert atmosphere;Wittig reaction;
Stage #2: 15-oxo-pentadecanoic acid methyl ester in tetrahydrofuran at -78 - 20;Inert atmosphere;stereoselective reaction;Wittig reaction;

References:

Rawling, Tristan;Duke, Colin C.;Cui, Pei H.;Murray, Michael [Lipids,2010,vol. 45,# 2,p. 159 - 165] Location in patent:experimental part

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