ChemicalBook CAS DataBase List CHEMBRDG-BB 5128501

CHEMBRDG-BB 5128501 synthesis

11synthesis methods

Product Name:CHEMBRDG-BB 5128501
CAS Number:5021-45-4
Molecular formula:C14H9BrN2
Molecular Weight:285.14

95-54-5 Synthesis

95-54-5
516 suppliers
$9.00/1g

99-73-0 Synthesis

99-73-0
233 suppliers
$10.00/1g

5021-45-4
30 suppliers
$60.00/500mg

Yield:5021-45-4 98%

Reaction Conditions:

with Bronsted acidic ionic liquid supported on nano silica in neat (no solvent) at 20; for 0.5 h;Green chemistry;

Steps:

General Procedure for the Synthesis of 2-Arylquinoxalines (3a-h)

General procedure: In 25 ml round-bottomed flask, a mixture of 1,2-phenylendiamine (1 mmol), a-bromoacetophenone(1 mmol) and BAILnano-SiO2 catalyst (35 mol%) was preparedand the reaction mixture was stirred at room temperature for the time shown inTable 2. The progress of the reaction was monitored by TLC. After completion of the reaction, ethyl acetate (5 mL) was added and the catalyst was separated by simplefiltration. The residue was dried over anhydrous Na2SO4 and after evaporation ofsolvent the pure product was obtained by recrystallization from ethanol.

References:

Daragahi, Seyed Arash Hosseini;Mohebat, Razieh;Mosslemin, Mohammad Hossein [Organic Preparations and Procedures International,2018,vol. 50,# 3,p. 301 - 313]