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ChemicalBook CAS DataBase List (BIS-TERT-BUTOXYCARBONYLMETHYL-AMINO)-ACETIC ACID
171557-31-6

(BIS-TERT-BUTOXYCARBONYLMETHYL-AMINO)-ACETIC ACID synthesis

3synthesis methods
-

Yield:171557-31-6 97%

Reaction Conditions:

with palladium 10% on activated carbon;hydrogen in methanol at 20; for 2 h;

Steps:

Synthesis of 12

Compound 11 (477 mg, 1.17 mmol) was used as a starting material. By the same synthetic procedure as that for 9, 12 (335 mg, 97%) was obtained as a pale yellow oil.

References:

Takahira, Ikuko;Fuchida, Hirokazu;Tabata, Shigekazu;Shindo, Naoya;Uchinomiya, Shohei;Hamachi, Itaru;Ojida, Akio [Bioorganic and Medicinal Chemistry Letters,2014,vol. 24,# 13,p. 2855 - 2858] Location in patent:supporting information