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ChemicalBook CAS DataBase List alpha,alpha,alpha-Trifluoro-o-toluoyl chloride
329-15-7

alpha,alpha,alpha-Trifluoro-o-toluoyl chloride synthesis

7synthesis methods
-

Yield:329-15-7 100%

Reaction Conditions:

with thionyl chloride for 2 h;Reflux;

Steps:

General synthetic procedure for the title compound 3a-w
General procedure: A mixture of various carboxylic acids (1.0mmol), an excess of thionyl chrolide (5mL) was refluxed for 2h and concentrated in vacuo to give corresponding acyl chloride (quant).

References:

Chen, Yin-Bo;Li, Ji-Ling;Shao, Xu-Sheng;Xu, Xiao-Yong;Li, Zhong [Chinese Chemical Letters,2013,vol. 24,# 8,p. 673 - 676]

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