AKOS BAR-2003 synthesis

4synthesis methods

Product Name:AKOS BAR-2003
CAS Number:389602-70-4
Molecular formula:C14H15N
Molecular Weight:197.28

623-03-0 Synthesis

623-03-0
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389602-70-4
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / 1,2-dimethoxyethane; water / 1 h / 150 °C / Inert atmosphere
2: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 °C / Reflux; Inert atmosphere

References:

Kang, Sunhee;Kim, Ryang Yeo;Seo, Min Jung;Lee, Saeyeon;Kim, Young Mi;Seo, Mooyoung;Seo, Jeong Jea;Ko, Yoonae;Choi, Inhee;Jang, Jichan;Nam, Jiyoun;Park, Seijin;Kang, Hwankyu;Kim, Hyung Jun;Kim, Jungjun;Ahn, Sujin;Pethe, Kevin;Nam, Kiyean;No, Zaesung;Kim, Jaeseung [Journal of Medicinal Chemistry,2014,vol. 57,# 12,p. 5293 - 5305]