6-TRIFLUOROMETHYL-1H-INDAZOLE-3-CARBOXYLIC ACID METHYL ESTER synthesis
- Product Name:6-TRIFLUOROMETHYL-1H-INDAZOLE-3-CARBOXYLIC ACID METHYL ESTER
- CAS Number:877773-17-6
- Molecular formula:C10H7F3N2O2
- Molecular Weight:244.17
121-17-5
8 suppliers
$19.00/250g
877773-17-6
38 suppliers
$156.00/50mg
Yield:-
Steps:
Multi-step reaction with 4 steps
1: potassium tert-butylate / tert-butyl alcohol / Reflux
2: dimethyl sulfoxide; sodium chloride / water / 120 °C
3: hydrogen / 5% Pd(II)/C(eggshell) / toluene / 20 °C / 760.05 Torr
4: tert.-butylnitrite; acetic acid / 2.17 h / 90 - 95 °C / Cooling with ice
References:
WO2011/5759,2011,A2
![Dimethyl [2-nitro-4-(trifluoromethyl)phenyl]malonate](/CAS/GIF/290825-52-4.gif)
290825-52-4
30 suppliers
$42.00/500mg
877773-17-6
38 suppliers
$156.00/50mg
13544-07-5
31 suppliers
$32.00/500mg
877773-17-6
38 suppliers
$156.00/50mg