(3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione synthesis
- Product Name:(3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione
- CAS Number:87721-89-9
- Molecular formula:C21H29N5O2
- Molecular Weight:383.49
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Yield:-
Steps:
Multi-step reaction with 2 steps
1: 95.9 percent / H2 / 10percent Pd-C/ 50percent H2O / tetrahydrofuran / 1.5 h / Ambient temperature
2: 67.2 percent / pyridine / 5 h / Heating
References:
Ishizumi;Kojima;Antoku [Chemical and Pharmaceutical Bulletin,1991,vol. 39,# 9,p. 2288 - 2300]
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