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ChemicalBook CAS DataBase List 7-BROMO-1,2,3,4-TETRAHYDROCYCLOPENTA[B]INDOLE
164736-47-4

7-BROMO-1,2,3,4-TETRAHYDROCYCLOPENTA[B]INDOLE synthesis

3synthesis methods
-

Yield: 92.3%

Reaction Conditions:

in ethanol for 10 h;Reflux;

Steps:

1.1-3
116.2 g (0.520 mol) of synthesized in [Scheme 2], 43.7 g (0.520 mol) of cyclopentanone and 1162.0 ml of ethanol were added to a 2 L round bottom flask and refluxed for 10 hours. After the reaction was completed, the reaction solution was concentrated and then column chromatography was used to obtain 120.0 g (yield 92.3%) of <1-c> .

References:

SFC Ltd.;Kim Si-in;Kim Nam-i KR102004387, 2019, B1 Location in patent:Paragraph 0279; 0292-0297

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