6-TRITYL-1,2,3,4-TETRA-O-ACETYL-BETA-D-GLUCOSE synthesis
- Product Name:6-TRITYL-1,2,3,4-TETRA-O-ACETYL-BETA-D-GLUCOSE
- CAS Number:37074-90-1
- Molecular formula:C33H34O10
- Molecular Weight:590.63
Yield:37074-90-1 68%
Reaction Conditions:
with dmap at 20;Large scale;
Steps:
2
(2) To step (1) the reaction system was added dropwise 1.7kg acetic anhydride, DMAP 17g was added dropwise after the completion of the addition, the system was stirred at room temperature overnight, point plate, the reaction was complete, the system was poured into ice water 3.5L, a large number The white solid was precipitated, suction filtered and the white solid was filtered with ethanol and heated to 45 ° C to dissolve it. The system was then slowly cooled to room temperature for crystallization. The mixture was filtered with suction to give 1.1 kg of a white solid compound 2 with a total yield of 68% The formula is as follows:
References:
CN107286207,2017,A Location in patent:Paragraph 0018
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