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ChemicalBook CAS DataBase List 6-Chlorohex-1-ene
928-89-2

6-Chlorohex-1-ene synthesis

15synthesis methods
-

Yield: 81%

Reaction Conditions:

with sodium in ethanol

Steps:

S.2.2 2)
To 1000 ml of absolute ethanol was added 4 g (0.174 mole) of sodium, and 20 g (0.125 mole) of diethyl malonate was then added thereto. Further, 14 g (0.118 mole) of 5-hexenyl chloride as obtained in (1) above was slowly added thereto, followed by refluxing for 2 hours. The reaction mixture was freed of the solvent by distillation, and the residue was distilled to obtain 23.2 g (yield: 81%) of diethyl 5-hexenylmalonate having a boiling point of 115°-116° C./3 mmHg.

References:

Takasago International Corporation US5141921, 1992, A

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