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ChemicalBook CAS DataBase List 6-AMINO-2-CHLORO-4-METHYLPYRIDINE-3-CARBONITRILE
51561-20-7

6-AMINO-2-CHLORO-4-METHYLPYRIDINE-3-CARBONITRILE synthesis

3synthesis methods
-

Yield:51561-20-7 90%

Reaction Conditions:

with ammonia in methanol at 150;Microwave irradiation;regioselective reaction;

References:

Chopko, Trevor C.;Han, Changho;Gregro, Alison R.;Engers, Darren W.;Felts, Andrew S.;Poslusney, Mike S.;Bollinger, Katrina A.;Morrison, Ryan D.;Bubser, Michael;Lamsal, Atin;Luscombe, Vincent B.;Cho, Hyekyung P.;Schnetz-Boutaud, Nathalie C.;Rodriguez, Alice L.;Chang, Sichen;Daniels, J. Scott;Stec, Donald F.;Niswender, Colleen M.;Jones, Carrie K.;Wood, Michael R.;Wood, Michael W.;Duggan, Mark E.;Brandon, Nicholas J.;Conn, P. Jeffrey;Bridges, Thomas M.;Lindsley, Craig W.;Melancon, Bruce J. [Bioorganic and Medicinal Chemistry Letters,2019,vol. 29,# 16,p. 2224 - 2228]

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