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ChemicalBook CAS DataBase List 5-TERT-BUTYL-2-METHYL-BENZOXAZOLE
40874-54-2

5-TERT-BUTYL-2-METHYL-BENZOXAZOLE synthesis

9synthesis methods
-

Yield:40874-54-2 96%

Reaction Conditions:

Stage #1: N-(5-(t-butyl)-2-hydroxyphenyl)acetamidewith trichlorophosphate in chloroform;Reflux;
Stage #2: with sodium hydroxide;lithium hydroxide monohydrate in chloroform; pH=8;Cooling with ice;

References:

Li, Ke-Lai;Du, Zong-Bo;Guo, Can-Cheng;Chen, Qing-Yun [Journal of Organic Chemistry,2009,vol. 74,# 9,p. 3286 - 3292] Location in patent:supporting information; experimental part