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ChemicalBook CAS DataBase List 5-Amino-1-naphthol
83-55-6

5-Amino-1-naphthol synthesis

9synthesis methods
1-Aminonaphthalene-5-sulfonic acid paste (Section 6.2) is added to molten sodium hydroxide at 200°C, and the reaction is completed by heating slowly to 250°C and maintaining this temperature for 3 h. After dilution and careful neutralization with hydrochloric acid, 5-amino-1-naphthol precipitates in 85 % yield (mp 192°C).
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Yield:83-55-6 95%

Reaction Conditions:

with hydrogen;5%-palladium/activated carbon in isopropyl alcohol at 50; under 6000.6 Torr; for 2 h;

Steps:

7 EXAMPLE 7 Reduction of 5-nitro-1-naphthol
In an autoclave was placed 1.9 g of 5-nitro-1-naphthol, 0.02 g of 5% Pd/C (containing 50% by weight of water), and 50 g of isopropanol, and the hydrogen pressure was set at 0.8 MPa. The reaction was carried out at 50 C. for 2 hours. After the reaction mixture was cooled, the catalyst was filtered off, and the reaction mass thus obtained was analyzed by gas chromatography. As a result, the content of 5-amino-1-naphthol produced was 1.5 g (yield 95%).

References:

Mitsui Chemicals, Inc. US2004/143137, 2004, A1 Location in patent:Page 5

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