Yield:-

Reaction Conditions:

with sodium carbonate for 3 h;Reflux;

Steps:

3.3c

The damp paste from stage 3b was stirred in 2M sodium carbonate(1 ,00OmI) and heated to reflux for 3 hours. Upon cooling to 25⁰C the product was collected by filtration and the damp paste stirred in acetone (2,000ml). The resulting product was dried to give a solid (132.7g).

References:

WO2010/41065,2010,A1 Location in patent:Page/Page column 20