4-FLUORO-3-METHOXYANILINE HYDROCHLORIDE synthesis
- Product Name:4-FLUORO-3-METHOXYANILINE HYDROCHLORIDE
- CAS Number:22510-10-7
- Molecular formula:C7H9ClFNO
- Molecular Weight:177.6
774232-94-9
0 suppliers
inquiry
22510-10-7
42 suppliers
$35.00/250mg
Yield:22510-10-7 71%
Reaction Conditions:
with hydrogenchloride in 1,4-dioxane at 20;
Steps:
34d
(tert-Butoxy)-N-(4-fluoro-3-methoxyphenyl)carboxamide (0.98 g, 4.06 mmol) (from Example 34c supra) was treated with 4 N hydrochloric acid in dioxane (20 ML) (Aldrich) overnight at room temperature.The resulting precipitate was collected by filtration and washed with dry ether to give 4-fluoro-3-methoxyphenylamine hydrochloric acid salt as a white, crystalline, solid. (Yield 512 mg, 71%).
References:
US2004/204427,2004,A1 Location in patent:Page/Page column 43