ChemicalBook CAS DataBase List 4-Chloro-7-nitrobenzofurazan

4-Chloro-7-nitrobenzofurazan synthesis

4synthesis methods

Product Name:4-Chloro-7-nitrobenzofurazan
CAS Number:10199-89-0
Molecular formula:C6H2ClN3O3
Molecular Weight:199.55

7116-16-7
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$36.00/1g

10199-89-0
211 suppliers
$15.00/250mg

Yield:10199-89-0 54%

Reaction Conditions:

with sodium nitrate;sulfuric acid at 0 - 85; for 0.583333 h;

Steps:

2.1.7. 4-Chloro-7-nitrobenzo[c][1,2,5]oxadiazole (3) [4]
2.1.7. 4-Chloro-7-nitrobenzo[c][1,2,5]oxadiazole (3) [4] A solution of NaNO3 (14.6 g, 172 mmol) in H2SO4 (250 g, 2.55 mol) was cooled to 0 °Cbefore 4-chlorbenzo[c][1,2,5]oxadiazole (4.59 g, 29.6 mmol) was added to the solution. Afterstirring for 5 min at 0 °C the reaction mixture was heated to 85 °C for 30 min. Thereafter icewater (250 mL) was added and cooled to 0 °C. The precipitate was filtered off andrecrystallized from an ethanol water mixture (1.6:1, 400 mL) to give 4-chloro-7-nitrobenzo[c][1,2,5]oxadiazole (3, 3.22 g, 16.1 mmol, 54%) as yellow needles.

References:

B?rgardts, Markus;Müller, Thomas J. J. [Beilstein Journal of Organic Chemistry,2017,vol. 13,p. 768 - 778] Location in patent:supporting information

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