4-Chloro-2-fluorotoluene synthesis
- Product Name:4-Chloro-2-fluorotoluene
- CAS Number:452-75-5
- Molecular formula:C7H6ClF
- Molecular Weight:144.57
148839-33-2
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$6.00/1g
452-75-5
256 suppliers
$16.00/25 g
Yield:452-75-5 11.9 mg
Reaction Conditions:
Stage #1:(5-chloro-2-methylphenyl)boronic acid with C27H23N4O6PdS;potassium carbonate in methanol;benzene at 23; for 10 h;
Stage #2: with Selectfluor in acetonitrile at 50; for 0.5 h;
References:
Furuya, Takeru;Kaiser, Hanns Martin;Ritter, Tobias [Angewandte Chemie - International Edition,2008,vol. 47,# 32,p. 5993 - 5996] Location in patent:supporting information; experimental part