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ChemicalBook CAS DataBase List 4''-CHLORO-2''-FLUOROACETOPHENONE
175711-83-8

4''-CHLORO-2''-FLUOROACETOPHENONE synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1.1: 2 h / 105 °C
2.1: aluminum (III) chloride / carbon disulfide / 0.5 h / 0 - 20 °C
2.2: 48 h / 0 °C / Reflux
3.1: hydrogenchloride / methanol; water / 4 h / Reflux
4.1: hydrogenchloride; sodium nitrite / water / 0.25 h / -5 - 5 °C
4.2: 1 h / 25 °C

References:

Suzhou Jingye Pharmaceutical And Chemical Co., Ltd.;Shen Jianwei;Wu Heming CN110668948, 2020, A

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