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ChemicalBook CAS DataBase List 4-AMINO-6-METHOXY-2-METHYLQUINOLINE
104217-23-4

4-AMINO-6-METHOXY-2-METHYLQUINOLINE synthesis

4synthesis methods
-

Yield:104217-23-4 82%

Reaction Conditions:

Stage #1: 4-chloro-6-methoxy-2-methylquinolinewith phenol at 180; for 1 h;
Stage #2: with ammonia at 180; for 5 h;
Stage #3: with sodium hydroxide in water at 20;

References:

Kakadiya, Rajesh;Dong, Huajin;Kumar, Amit;Narsinh, Dodia;Zhang, Xiuguo;Chou, Ting-Chao;Lee, Te-Chang;Shah, Anamik;Su, Tsann-Long [Bioorganic and Medicinal Chemistry,2010,vol. 18,# 6,p. 2285 - 2299] Location in patent:supporting information; experimental part

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