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ChemicalBook CAS DataBase List 4,4'-DIMETHOXYBENZIL
1226-42-2

4,4'-DIMETHOXYBENZIL synthesis

12synthesis methods
-

Yield:1226-42-2 98%

Reaction Conditions:

with selenium(IV) dioxide in dimethyl sulfoxide at 170; for 0.0166667 h;Microwave irradiation;

Steps:

4.2.2. Experimental Procedure for Ethanediones 12 [36]

General procedure: Selenium dioxide (1.5 mmol) was added into a solutionof ethanone derivatives 11 (1 mmol) in DMSO (1.5 mL) andirradiated in the microwave oven for 1 min at 170C. The hotmixture was filtered to remove the selenium metal and thefiltrate was purified by column chromatography in silica gelusing EtOAc/hexanes 7:3 as eluent.

References:

Sangi, Diego P.;Cominetti, Márcia R.;Becceneri, Amanda B.;Resende, Flavia A.;Varanda, Eliana A.;Montanari, Carlos A.;Paix?o, Marcio W.;Corrêa, Arlene G. [Medicinal Chemistry,2015,vol. 11,# 8,p. 736 - 746]

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