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ChemicalBook CAS DataBase List 4,4-DIFLUOROCYCLOHEXYLAMINE HYDROCHLORIDE
675112-70-6

4,4-DIFLUOROCYCLOHEXYLAMINE HYDROCHLORIDE synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 3-chloro-benzenecarboperoxoic acid; diethylamino-sulfur trifluoride; sodium tetrahydroborate / water; Petroleum ether; ethyl acetate
2: hydrogenchloride

References:

AGIOS PHARMACEUTICALS, INC;Popovici-Muller, Janeta;Salituro, Francesco G.;Saunders, Jeffrey O.;Cai, Zhenwei;Yan, Shunqi;Zhou, Ding US2015/87600, 2015, A1

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