ChemicalBook CAS DataBase List 3-(PHENYLSULFONYL)PROPIONIC ACID

3-(PHENYLSULFONYL)PROPIONIC ACID synthesis

13synthesis methods

Product Name:3-(PHENYLSULFONYL)PROPIONIC ACID
CAS Number:10154-71-9
Molecular formula:C9H10O4S
Molecular Weight:214.24

79-10-7 Synthesis

79-10-7
698 suppliers
$20.16/100 mL

80-17-1 Synthesis

80-17-1
159 suppliers
$23.00/25g

10154-71-9
132 suppliers
$8.00/1g

Yield: 83%

Reaction Conditions:

in water at 120; for 24 h;Sealed tube;

Steps:

3 Example 3:
Take a 38mL thick wall pressure tube,Benzenesulfonylhydrazide (2 mmol, 355.2 mg) was added thereto,A solution of acrylic acid (3 mmol, 0.2 mL) was then added to the solution,Add 4 mL of water, add the appropriate type of magnet,Check that the rubber gasket of the sealing plug is intact.Then, tighten the screws of the sealed tube, 120 oil bath heating reaction 24h.After the reaction, stop heating, natural cooling to room temperature,Slowly unscrew the plug,The pH of the solution was adjusted to 6, EtOAc (50 mL x 3) with 1 mol / L HCl,The organic phases were combined and the organic phase was washed with saturated brine,The organic phase was collected, dried over anhydrous sodium sulfate for half an hour,Spin off the solvent to get 3 - benzenesulfonyl propionic acid, white crystal powder 361.3 mg, the yield of 83%.

References:

University of Jinan;Gao Lingfeng;Li Wei;Zheng Gengxiu;Feng Xue;Han Xiujiao;Han Xinyu;Liu Jingbao;Wang Bin CN106631927, 2017, A Location in patent:Paragraph 0016

108-31-6 Synthesis