ChemicalBook CAS DataBase List 3-Bromostyrene

3-Bromostyrene synthesis

12synthesis methods

Product Name:3-Bromostyrene
CAS Number:2039-86-3
Molecular formula:C8H7Br
Molecular Weight:183.05

3132-99-8 Synthesis

3132-99-8
488 suppliers
$5.00/10g

2065-66-9
315 suppliers
$5.00/5g

2039-86-3
155 suppliers
$15.00/1g

Yield:2039-86-3 100%

Reaction Conditions:

with potassium carbonate in 1,4-dioxane;water at 100; for 12 h;Inert atmosphere;

Steps:

4.1 1-bromo-3-vinylbenzene
Bromobenzaldehyde 4a (10 g, 54.05 mmol) was dissolved in a mixed solvent of 102 mL of dioxane and water (v / v = 50: 1), potassium carbonate (18.64 g, 135 mmol) and methyltriphenylphosphonium iodide (43.70g, 108.11 mmol),The temperature was raised to 100 ° C and the reaction was stirred for 12 hours. Filtered and the filter cake was washed with 200 mL of n-hexane and ethyl acetate (V / V = 50: 1) mixed solvent. 1-bromo-3-vinylbenzene 4b (10 g, yellow liquid), yield: 100.0%.

References:

SHANGHAI HENGRUI PHARM CO LTD;JIANGSU HENGRUI MEDICINE CO LTD;Lyu, HEJUN;DONG, QING;FEI, HONGBO;JIANG, HONGJIAN;SONG, PENG CN103030646, 2016, B Location in patent:Paragraph 0207-0213

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52780-14-0 Synthesis