3-Bromo-5-chlorosalicylaldehyde synthesis
- Product Name:3-Bromo-5-chlorosalicylaldehyde
- CAS Number:19652-32-5
- Molecular formula:C7H4BrClO2
- Molecular Weight:235.46
635-93-8
350 suppliers
$6.00/5g
19652-32-5
212 suppliers
$10.00/5g
Yield: 99%
Reaction Conditions:
with N-Bromosuccinimide in N,N-dimethyl-formamide at 20; for 72 h;
Steps:
15
Description 15 (D15) 3-bromo-5-chloro-2-hvdroxybenzaldehydeA solution of 5-chloro-2-hydroxybenzaldehyde (5.00 g, 31.93 mmol) and N- bromosuccinamide (5.68 g, 31.93 mmol) in dry DMF (64 ml) was stirred at room temperature under an atmosphere of argon for 72 hours (over the weekend). The reaction was monitored by LC-MS. The reaction mixture was diluted with EtOAc and washed with
References:
GLAXO GROUP LIMITED WO2008/98978, 2008, A2 Location in patent:Page/Page column 37-38
