3-Amino-5-mercapto-1,2,4-triazole synthesis
- Product Name:3-Amino-5-mercapto-1,2,4-triazole
- CAS Number:16691-43-3
- Molecular formula:C2H4N4S
- Molecular Weight:116.14
142-46-1
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16691-43-3
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Yield:-
Reaction Conditions:
with sodium hydroxide in water; for 3 h;Reflux;
Steps:
General procedure for synthesis of 2-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylthio)acetohydrazide (6)
(2) NaOH (225g, 5.62mol) was dissolved in water (960mL). 2 was then added and the solution was refluxed for 3h. After cooling, the pH value of the solution was adjusted to 1 using hydrochloric acid. After that the solid was precipitated and recrystallization from methanol gave 3 as colorless crystals.
References:
Luo, Yin;Zhang, Shuai;Liu, Zhi-Jun;Chen, Wu;Fu, Jie;Zeng, Qing-Fu;Zhu, Hai-Liang [European Journal of Medicinal Chemistry,2013,vol. 64,p. 54 - 61]
108302-28-9
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16691-43-3
372 suppliers
$15.00/5g