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ChemicalBook CAS DataBase List 3,5-bis(pyridin-4-yl)-4-amino-1,2,4-triazole
38634-05-8

3,5-bis(pyridin-4-yl)-4-amino-1,2,4-triazole synthesis

4synthesis methods
-

Yield: 86%

Reaction Conditions:

with hydrazine hydrate in ethanol at 120; for 72 h;Autoclave;

Steps:

Synthesis of 4-abpt.
A mixture of 4-cyanopyridine (10mmol, 1.04g) and hydrazine monohydrate (80% 1.5mL) in 2mL C2H5OH was sealed in a 23mL Teflon-lined stainless autoclave and heated at 120°C for 3days and subsequently cooled to room temperature at a rate of 1.25°Ch-1. Colorless crystals of 4-abpt were collected by washing with C2H5OH, and dried in air. Yield: 86%. Anal. Calcd for C12H10N6: C 60.50; N 35.27; H 4.23 Found: C 60.67; N 35.01; H 4.32%.

References:

Chen, Kai-Hong;Deng, Zhao-Yang;Le, Jin-Feng;Li, Ling;Xie, Xin;You, Sheng-Yong;Zou, Ji-Yong [Inorganica Chimica Acta,2020,vol. 513]

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