ChemicalBook CAS DataBase List 3,4-DIMETHOXY-5-NITRO-BENZALDEHYDE

3,4-DIMETHOXY-5-NITRO-BENZALDEHYDE synthesis

6synthesis methods

Product Name:3,4-DIMETHOXY-5-NITRO-BENZALDEHYDE
CAS Number:22027-96-9
Molecular formula:C9H9NO5
Molecular Weight:211.17

120-14-9 Synthesis

120-14-9
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22027-96-9
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$368.00/10g

Yield: 98%

Reaction Conditions:

with nitric acid;acetic acid at 20; for 12 h;

Steps:

10 Example 10: Synthesis of 3,4-Dimethoxy-5-nitrobenzaldehyde (13a)
Dissolve 30mmol of 3,4-dimethoxybenzaldehyde in 20mL of glacial acetic acid, slowly add 30mL of concentrated nitric acid dropwise at room temperature, continue stirring for 12h, check the reaction process by TLC, after the reaction is complete, pour the reaction solution into a large amount of water , A pale yellow solid was precipitated, filtered and washed repeatedly with clear water, and dried to obtain the product with a yield rate of 98%.

References:

Wuhan Chemical New Materials Industry Technology Institute Co., Ltd.;Liu Peng;Yan Yezhou CN112079741, 2020, A Location in patent:Paragraph 0102-0103