3-(2,6-DICHLOROPHENYL)-5-METHYL-4-ISOXAZOLECARBONITRILE synthesis
1synthesis methods
- Product Name:3-(2,6-DICHLOROPHENYL)-5-METHYL-4-ISOXAZOLECARBONITRILE
- CAS Number:21486-28-2
- Molecular formula:C11H6Cl2N2O
- Molecular Weight:253.08
Yield:21486-28-2 10%
Reaction Conditions:
Stage #1: but-2-enenitrile;2,6-dichlorobenzohydroximoyl chloridewith triethylamine in tetrahydrofuran at 20 - 67; for 4 h;
Stage #2: with nickel(IV) oxide in benzene;Heating;Further stages.;
References:
Easton;Heath;Hughes;Lee;Savage;Simpson;Tiekink;Vuckovic;Webster [Journal of the Chemical Society. Perkin Transactions 1 (2001),2001,# 10,p. 1168 - 1174]