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ChemicalBook CAS DataBase List 2-Methoxypropene
116-11-0

2-Methoxypropene synthesis

12synthesis methods
-

Yield:116-11-0 93.6%

Reaction Conditions:

with quinoline at 30 - 105; under 12751.3 Torr;Pyrolysis;Temperature;

Steps:

1-5 Example 3, continuous preparation of 2-methoxypropene
10 g of acidic ceramic filler was filled into a fixed bed reactor, heated to 105 ° C, 1.0 g of cocatalyst quinoline was dissolved in 10 kg of 2,2-dimethoxypropane, and the mixed solution was heated and vaporized by a preheater. Continuous cracking through a fixed bed reactor to control the feed rate of 2,2-dimethoxypropane to 20 g/min, cleavage products (2-methoxypropene, methanol and unreacted 2,2-dimethoxy a mixture of propane having a mass content of 65.7%, 32.5%, and 0.8% in sequence is subjected to rectification separation at 30 ° C to 60 ° C through a rectification column, and 2-methoxypropene is obtained at the top of the rectification column. a mixture of partially unreacted 2,2-dimethoxypropane and cleavage of methanol is obtained from the azeotrope column of methanol; the mixture of 2,2-dimethoxypropane and methanol obtained in the column is passed through The membrane was subjected to methanol removal at 15 ° C and 1.7 MPa to recover 2,2-dimethoxypropane, and the above 2,2-dimethoxypropane was transferred to a fixed bed reactor by a metering pump. The 2-methoxypropene and methanol azeotrope was passed through a nanofiltration membrane, and methanol was removed at 10 ° C and 1.5 MPa to obtain 2-methoxypropene having a purity of 99.3%, and the product yield was about 93.6%.

References:

Chinese Academy Of Sciences Chemical Institute;University of the Chinese Academy of Sciences;Zhejiang Pharmaceutical Co., Ltd. Xinchang Pharmaceutical Factory;Song Weiguo;Zhai Dewei;Cao Changyan;Huo Hongfei;Liu Dong;Zhao Jiawei CN110240540, 2019, A Location in patent:Paragraph 0033; 0034

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