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ChemicalBook CAS DataBase List 2-HYDRAZINOBENZOTHIAZOLE
615-21-4

2-HYDRAZINOBENZOTHIAZOLE synthesis

13synthesis methods
-

Yield:615-21-4 93%

Reaction Conditions:

with hydrazine hydrate in ethanol at 80; for 5 h;

Steps:

2.2.5. Preparation and characterization of 7

To a solution of 2-chlorobenzo[d]thiazole (0.169 g, 1 mmol) inethanol, N2H4H2O (80%, 5 mmol) was dropwise added withrefluxing at 80 °C for 5 h. When cooled to room temperature, themixture was filtered, washed and recrystallized with ethanol. Thewhite solid thus obtained and dried under vacuum to get compound7 (0.154 g) in 93% yield. 1H NMR (DMSO-d6, 600 MHz):δ(ppm): 9.01 (s, 1H), 7.68 (d, J 7.8 Hz, 1H), 7.32 (d, J 8.0 Hz, 1H),7.20 (t, J 7.6 Hz, 1H), 6.98 (t, J 7.5 Hz, 1H), 5.03 (s, 2H). 13C NMR(DMSO-d6, 151 MHz): δ (ppm): 174.4, 153.9, 130.9, 125.8, 121.4,120.7, 118.3 (Fig. S5).

References:

zhang, Huifang;Yin, Caixia;Liu, Tao;Chao, Jianbin;Zhang, Yongbin;Huo, Fangjun [Dyes and Pigments,2017,vol. 146,p. 344 - 351]

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