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ChemicalBook CAS DataBase List 2-Chloro-4-(trifluoromethyl)pyridine
81565-18-6

2-Chloro-4-(trifluoromethyl)pyridine synthesis

9synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: sodium nitrite; hydrogenchloride / water / 20 °C / Industrial scale
2: chlorine / 150 °C / Industrial scale
3: hydrogen fluoride / 200 °C / 37503.8 Torr / Autoclave; Industrial scale

References:

Inner Mongolia Jiaruimi Fine Chemical Co., Ltd.;Yang Shaogang;Si Yongli CN107151229, 2017, A

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