2-Chloro-1,3-dimethylimidazolidinium chloride synthesis
- Product Name:2-Chloro-1,3-dimethylimidazolidinium chloride
- CAS Number:37091-73-9
- Molecular formula:C5H10Cl2N2
- Molecular Weight:169.05
80-73-9
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$8.00/25g
37091-73-9
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$7.00/1g
Yield:37091-73-9 96.6%
Reaction Conditions:
with phosgene in tetrachloromethane at 5 - 50; for 5.5 h;
Steps:
preparation of chloro-1,3-dimethyl-2-chloroimidazoline
For 1000 ml three port in the reaction bottle, by adding 1,3-dimethyl-2-imidazolidinone (34.2 g, 0.3 mol), carbon tetrachloride (400 ml), stirring slowly dropwise solid phosgene carbon tetrachloride solution (containing solid phosgene 30 g, 0.1 mole, carbon tetrachloride 100 ml), the reaction mixture is kept below 5 °C, violent mixing 0.5 hours, the reaction at room temperature 1 hour, heating to 50 °C, maintain 4 hours. To be the reaction product is cooled to room temperature, filter, a small amount of carbon tetrachloride washing, get a pure white crystalline product chloropivaloyl 1,3-dimethyl-2-chlorotrifluoromethylbenzene imidazoline 49 g, yield of 96.6%,
References:
Beijing Chengyu Pharmaceutical Co., Ltd.;Song, Ye;Wang, Daolin;Wang, Yuping CN105367478, 2016, A Location in patent:Paragraph 0021; 0027; 0028
80-73-9
570 suppliers
$8.00/25g
79-37-8
475 suppliers
$17.67/10gm:
37091-73-9
203 suppliers
$7.00/1g