2-Bromo-4,5-difluorobenzonitrile synthesis
- Product Name:2-Bromo-4,5-difluorobenzonitrile
- CAS Number:64695-82-5
- Molecular formula:C7H2BrF2N
- Molecular Weight:218
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Yield:-
Steps:
Multi-step reaction with 2 steps
1.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 2.5 h / 20 °C / Inert atmosphere
1.2: 0.25 h / 20 °C / Inert atmosphere
2.1: pyridine; trifluoroacetic anhydride / 1,4-dioxane / 4.5 h / 20 °C / Cooling with ice
References:
UNIVERSITY OF HAWAII WO2021/16333, 2021, A1
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