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ChemicalBook CAS DataBase List 2-BIPHENYL-(3'-METHOXY)CARBOXYLIC ACID
38087-96-6

2-BIPHENYL-(3'-METHOXY)CARBOXYLIC ACID synthesis

10synthesis methods
610-97-9 Synthesis
Methyl 2-iodobenzoate

610-97-9
407 suppliers
$9.00/1g

10365-98-7 Synthesis
3-Methoxyphenylboronic acid

10365-98-7
414 suppliers
$9.00/10g

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Yield:38087-96-6 100%

Reaction Conditions:

Stage #1: o-iodo-methyl-benzoic acid;3-methoxyphenylboronic acidwith bis-triphenylphosphine-palladium(II) chloride;potassium phosphate in 1,2-dimethoxyethane;water at 180; for 0.25 h;Microwave irradiation;
Stage #2: with sodium hydroxide in methanol;water at 150; for 0.0833333 h;Microwave irradiation;

References:

Tobisu, Mamoru;Yasui, Kosuke;Aihara, Yoshinori;Chatani, Naoto [Angewandte Chemie - International Edition,2017,vol. 56,# 7,p. 1877 - 1880][Angew. Chem.,2017,vol. 129,p. 1903 - 1906] Location in patent:supporting information

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