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ChemicalBook CAS DataBase List 2,6-DIMETHYLBENZENESULFONYL CHLORIDE
2905-29-5

2,6-DIMETHYLBENZENESULFONYL CHLORIDE synthesis

3synthesis methods
-

Yield: 84%

Steps:

270.1 4-{3-[1-benzhydryl-5-chloro-2-(2-{[(2,6-dimethylphenyl)sulfonyl]amino}ethyl)-1H-indol-3-yl]propyl}benzoic acid
Step 1: 2,6-Dimethylbenzenesulfonyl chloride was prepared from 2-bromo-1,3-dimethylbenzene according to the procedure in Example 18, Step 1-2. The reaction gave product as a white solid in 84% yield. 1H NMR (400 MHz, DMSO-D6) ppm 2.54 (s, 6 H), 6.94 (d, J=7.33 Hz, 2 H), 7.02 (m, 1 H).

References:

Wyeth US2003/144282, 2003, A1

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