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ChemicalBook CAS DataBase List 2,5-DICHLORO-3-METHYLPYRIDINE
59782-90-0

2,5-DICHLORO-3-METHYLPYRIDINE synthesis

4synthesis methods
-

Yield:-

Reaction Conditions:

with chlorine;molybdenum in benzene at 40 - 50;Temperature;Solvent;Reagent/catalyst;

Steps:

1.1-5.1
(1): Put 250g of benzene and 55g of picoline in a 500ml four-necked flask, stir and raise the temperature to 40-45°C to completely dissolve the picoline, and control the temperature at about 50°C.Add 1.0g of metallic molybdenum intermittently, and after the addition is complete, pass chlorine at this temperature for 11-12 hours. Convert the picoline to 2,3-dichloro-5-picoline for use.

References:

Jiangsu Youjia Plant Protection Co., Ltd.;Wu Xiaoju;Kong Yong;Xie Bangwei;Peng Da;Liu Yanpeng CN111187203, 2020, A Location in patent:Paragraph 0025-0027; 0030-0032; 0035-0037; 0040-0042; 0045

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