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7142-94-1

2-[(4-chlorophenyl)carbamoyl]benzoic acid synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 42 percent / DIEA; PyBOP / dimethylformamide / 24 h / 60 °C
2: 78 percent / aq. NaOH / 1 h / 80 °C

References:

Tondi, Donatella;Morandi, Federica;Bonnet, Richard;Costi, M. Paola;Shoichet, Brian K. [Journal of the American Chemical Society,2005,vol. 127,# 13,p. 4632 - 4639]