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ChemicalBook CAS DataBase List 2-(1,3-BENZODIOXOL-5-YLOXY)NICOTINIC ACID
214758-41-5

2-(1,3-BENZODIOXOL-5-YLOXY)NICOTINIC ACID synthesis

1synthesis methods
-

Yield:-

Reaction Conditions:

Stage #1: Sesamol;ethyl 2-chloronicotinatewith cesium carbonate in 1,4-dioxane; for 16 h;Heating / reflux;
Stage #2: with lithium hydroxide in 1,4-dioxane;water; for 4 h;Heating / reflux;

References:

EP1229034,2002,A1 Location in patent:Page 118

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