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125760-26-1

N-(9-Fluorenylmethoxycarbonyl)-L-serine Phenacyl Ester synthesis

1synthesis methods
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Yield:125760-26-1 68%

Reaction Conditions:

Stage #1: N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serinewith N-cyclohexyl-cyclohexanamine in ethyl acetate at 20; for 2 h;
Stage #2: α-bromoacetophenonewith triethylamine in N,N-dimethyl-formamide at 20; for 3.5 h;

References:

Yates, Lisa M.;Fiedler, Dorothea [ACS Chemical Biology,2016,vol. 11,# 4,p. 1066 - 1073]