6,7-DIMETHOXY-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER synthesis
- Product Name:6,7-DIMETHOXY-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
- CAS Number:120372-85-2
- Molecular formula:C14H15NO5
- Molecular Weight:277.27
Yield:120372-85-2 66%
Reaction Conditions:
Stage #1: diethyl 2-ethoxymethylenemalonate;3,4-dimethoxyaniline at 120; for 1 h;
Stage #2: in diphenylether at 280; for 1 h;
References:
Kubo, Kazuo;Ohyama, Shin-Ichi;Shimizu, Toshiyuki;Takami, Atsuya;Murooka, Hideko;Nishitoba, Tsuyoshi;Kato, Shinichiro;Yagi, Mikio;Kobayashi, Yoshiko;Iinuma, Noriko;Isoe, Toshiyuki;Nakamura, Kazuhide;Iijima, Hiroshi;Osawa, Tatsushi;Izawa, Toshio [Bioorganic and Medicinal Chemistry,2003,vol. 11,# 23,p. 5117 - 5133]
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